Deborah Woo entered the direct selling industry in 1990 when she joined Amway Hong Kong as a distributor relations manager. She would then go on to become director of sales for Caring International (Hong Kong) Limited in 1996 where she headed up multifunctional teams in operations, distributor relations, and marketing.

Deborah joined USANA as general manager of USANA Hong Kong in 1999 with a mission to establish and develop the local market–the company's first expansion into Asia. In 2003, she was promoted to regional general manager and became responsible for the Hong Kong, Taiwan, and Singapore markets. As USANA continued to expand in the region, Deborah was appointed vice president of Greater China and East Asia in 2005 and, subsequently, reappointed to her current role as vice president of Greater China in 2006 for the sake of focusing on the development of the Greater China market.